Pellagra with Skin Eruptions

Olanzapine-induced Skin Eruptions

Adverse cutaneous reactions are known to occur with psychotropic medications, which may lead to poor drug compliance. As compared to other group of psychotropics, there is relatively scarce literature on olanzapine-induced skin eruptions. We present a case of a 39-year-old man diagnosed with first episode mania and alcohol dependence syndrome who was started on tablet olanzapine which leads to ...

Familial pellagra-like skin rash with neurological manifestations.

A 14-year-old boy of Arabic origin presented with a pellagra-like rash and neurological manifestations including ataxia, dysarthria, nystagmus, and coma. There was a striking response to oral nicotinamide. The laboratory findings were not typical of Hartnup disease: aminoaciduris and indicanuria were absent and there was no evidence of tryptophan malabsorption. Tryptophan loading did not induce...

Itching in Syphilitic Skin Eruptions

Patient with AIDS and acute circinate skin eruptions.

Figure 1. A polycyclic, papular eruption on the face. A 24-year-old transgender woman with Treacher-Collins syndrome (mandibulofacial dysostosis) and AIDS (CD4 + cell count, 151 cells/mm 3) presented with a 1-month history of a pruritic, mildly erythematous, polycyclic papular eruption distributed diffusely over her face. She had no history of any similar eruptions and no history of facial impl...

RASopathic Skin Eruptions during Vemurafenib Therapy

PURPOSE Vemurafenib is a potent inhibitor of V600 mutant BRAF with significant impact on progression-free and overall survival in advanced melanoma. Cutaneous side effects are frequent. This single-center observational study investigates clinical and histological features of these class-specific cutaneous adverse reactions. PATIENTS AND METHODS Patients were all treated with Vemurafenib 960 m...